Description
Magnesium Sulfate Manufacturer – Magnesium Sulfate is a naturally occurring mineral that doctors use to control low magnesium levels in the blood. Magnesium Sulfate Injection is very useful against pediatric acute nephritis. Additionally, it effectively works to prevent seizures in severe pre-eclampsia, eclampsia, or toxemia of pregnancy. Also, Magnesium Sulfate is available in the market under the brand name – MgSO4.
Dosage of Magnesium Sulfate And Its Considerations
Here is the ideal dose of Magnesium Sulfate Injection:
- 40 mg/ml for kids
- 80 mg/ml for adults
Here are the dosage considerations that need to be kept in mind:
Hypomagnesemia
Adult:
- Mild – 4 doses (1 gram each) intramuscularly (IM) after every 6 hours
- Severe – 5 grams each intravenously (IV) for over 3 hours
- Maintenance – 30 to 60 mg per kg per day (IV)
Kids:
- Intramuscular/Intravenous (IM/IV) – 25 to 50 mg per kg after every 4 to 6 hours for 3 to 4 doses
- Oral – 100 to 200 mg per kg after every 6 hours
Toxemia of Pregnancy
- Injected to avoid seizures related to pre-eclampsia
- 4 to 5 grams intravenously (diluted in 250 ml NS/D5W) in a blend with (a) up to 10 g (10 mL of undiluted 50% solution) divided & administered intramuscularly (IM) into each buttock; or (b) after initial IV dose, 1 to 3 g/hour IV
Side Effects of Using Magnesium Sulfate Injection
Here are a few side effects that you may experience while taking Magnesium Sulfate Injection:
- Circulatory Collapse
- Respiratory Paralysis
- Low Body Core Temperature
- Excess Fluid in Lungs
- Poor Reflexes
Which Drugs Interact with Magnesium Sulfate Injection?
If your doctor has prescribed you to use this medicine, you are supposed to inform him if you are any other drug without failing. It is very important as 2 different drugs may interact and show adverse effects on your body. Here are a few drugs that may interact with Magnesium Sulfate Injection:
- demeclocycline
- eltrombopag
- lymecycline
- oxytetracycline
- tetracycline
Warnings Related to Magnesium Sulfate Injection
Here are a few things that you should definitely keep in mind while using it:
- This medicine carries magnesium sulfate. Do not take MgSO4 if you are allergic or sensitive to magnesium sulfate.
- Keep it away from children as it is very harmful to them.
- In case of overdose, get medical help immediately or contact Poison Control Centre
Wrapping Up
Magnesium Sulphate Injection is a very effective medicine that is used to treat the low levels of magnesium in the blood. So, if you are suffering from low magnesium levels in the blood, you can use it but only under the guidance of a medical practitioner. But you need to take care that the dosage of magnesium sulfate differs in children and in adults. Also, it may interact with other drugs such as demeclocycline, eltrombopag, and lymecycline. If you are already taking any of these, inform your doctor so that he can take proper precautionary action.